Category: Illnesses and disabilities
Introduction and description
Osteoporosis ("porous bones", from Greek: οστούν/ostoun meaning "bone" and πόρος/poros meaning "pore") is a progressive bone disease that is characterized by a decrease in bone mass and density which can lead to an increased risk of fracture. In osteoporosis, the bone mineral density (BMD) is reduced, bone microarchitecture deteriorates, and the amount and variety of proteins in bone are altered. It is commonly believed to be a disease that only afflicts the elderly, but it can afflict people from all age ranges depending on the cause. Children can be afflicted with osteoporosis - especially those on certain pharmaceuticals.
The person loses height, and gradually becomes bent with a characteristic 'hump'. The bones become more brittle and fragile and fractures are more frequent.
Osteoporosis is …. a major public health problem in EC member states because of the high incidence of fragility fractures, especially hip and vertebral fracture. In EC member states the high incidence of osteoporotic fractures leads to considerable mortality, morbidity, reduced mobility and decreased quality of life. In 1995 the number of hip fractures in 15 countries of EC has been 382,000 and the estimated total care cost of about 9 billion of ECUs. PMID: 11683549
- Vitamin supplements - Overdosing on vitamin supplements has been shown to produce osteoporosis, particularly overdosing on Vitamin A - and increases the risk of bone fractures, particularly hip fractures and hip problems because it suppresses bone building while simultaneously stimulating bone breakdown. “Indeed, a study by Forsmo et al. shows a correlation between low bone mineral density and too high intake of vitamin A”
- Colas and soft drinks - because they can leach minerals and may result in overdose of some vitamins
- Nutritional deprivation - although many sources say it is a lack of calcium that is the problem, it can also be an overdose of vitamin A via certain foods - an imbalance. For example, cod liver oil, liver, orange vegetables (carrots, pumpkin, squash, sweet potatoes), dairy products (butter, cheese, milk) and eggs. A diet in which these foods predominate may actually contribute to osteoporosis even though some of the foods contain calcium. But calcium deficiency can be a problem.
The daily average calcium intake in Europe has been evaluated in the SENECA study concerning the diet of elderly people from 19 towns of 10 European countries. In about one third of subjects the dietary calcium intake results were very low, between 300 and 600 mg/day in women, and 350 and 700 mg/day in men. In 1998, the expert committee of the European Community in the Report on Osteoporosis-Action on prevention, has given the recommended daily dietary allowances (RDA) for calcium at all stage of life. For the elderly population, above age 65 the RDA is 700-800 mg/day. The main source of calcium in the diet are dairy products (milk, yoghurts and cheese) fish (sardines with bones), few vegetables and fruits. The optimal way to achieve adequate calcium intake is through the diet. PMID: 11683549
- Pharmaceuticals - numerous pharmaceuticals can result in osteoporosis. This LINK takes you to the eHealthme website which lists all the pharmaceuticals that are implicated in osteoporosis. The list has been compiled from Adverse Drug Reports submitted to the FDA and SEDA. Many pharmaceuticals that cause calcium imbalance contribute to osteoporosis development. For example
- Diuretics such as Thiazide
- Calcium channel blockers,
- Alcoholism treatments
- Antacids and heartburn treatments,
- some anti-arrhythmia drugs
- Laxatives - prolonged use of medications/laxatives containing magnesium
- Chelation Therapy - for metal exposure, particularly EDTA
- Osteoporosis drugs - such as Bisphosphonates and Denosumab.
- Proton pump inhibitors
- Blood thinners – long-term use of heparin is associated with a decrease in bone density, and warfarin (and related coumarins) have been linked with an increased risk in osteoporotic fracture in long-term use
- Epilepsy drugs
- Diabetes drugs - for example, Thiazolidinediones (used for diabetes) – rosiglitazone and possibly pioglitazone, inhibitors of PPARγ, have been linked with an increased risk of osteoporosis and fracture
Osteoporosis, a skeletal disorder characterized by compromised bone strength and an increased risk of fractures, is an important paediatric disorder that involves almost all paediatric subspecialties. …. The most common causes of secondary osteoporosis include chronic systemic inflammation, glucocorticoid use and neuromuscular disabilities. PMID: 23591487
- Smoke inhalation - for example
Smoking is a major risk factor for osteoporosis and fracture, but the mechanism through which smoke causes bone loss remains unclear. Here, we show that the smoke toxins benzo(a)pyrene (BaP) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) interact with the aryl hydrocarbon receptor (Ahr) to induce osteoclastic bone resorption through the activation of cytochrome P450 1a/1b (Cyp1) enzymes. BaP and TCDD enhanced osteoclast formation in bone marrow cell cultures and gavage with BaP stimulated bone resorption and osteoclastogenesis in vivo. PMID:23776235
- Bacterial infection - of various sorts, not just direct infection internally, but via tooth decay, for example
The association between osteoporosis and jawbones remains an argument of debate. Both osteoporosis and periodontal diseases are bone resorptive diseases; it has been hypothesized that osteoporosis could be a risk factor for the progression of periodontal disease and vice versa. .. it is supposed that the osteoporosis-related bone mass density reduction may accelerate alveolar bone resorption caused by periodontitis, resulting in a facilitated periodontal bacteria invasion. Invading bacteria, in turn, may alter the normal homeostasis of bone tissue, increasing osteoclastic activity and reducing local and systemic bone density by both direct effects (release of toxins) and/or indirect mechanisms (release of inflammatory mediators). PMID: 23229255
- Lack of sunshine - One of the vitamins needed to make bone is vitamin D and one of the major sources of vitamin D is the sun. If the elderly [or even not so elderly] do not go outside much, they could suffer from Vitamin D deficiency. [ Note that Vitamin supplements are not the answer]
The two nutrients essential for bone health are calcium and vitamin D....a chronic and severe vitamin D deficiency leads to osteomalacia, a metabolic bone disease characterized by a decreased mineralization of bone. Vitamin D insufficiency, the preclinical phase of vitamin D deficiency, is most commonly found in the elderly. The major causes of vitamin D deficiency and insufficiency are decreased renal hydroxylation of vitamin D, poor nutrition, scarce exposition to sunlight and a decline in the synthesis of vitamin D in the skin.....Adequate sunlight exposure may prevent and cure vitamin D insufficiency. PMID: 11683549
- Kidney disease - for the reasons stated above
- Diarrhoea – causing electrolyte imbalance
- Nausea and vomiting - ditto
- Thyroid gland damage - Calcium is tightly regulated by the parathyroid hormone (PTH). In response to low calcium levels, PTH induces the kidneys to reabsorb calcium, the kidneys to increase production of calcitriol (the active form of vitamin D) thereby increasing intestinal absorption of calcium. These actions lead to a re-balance in the blood calcium levels. However, in the setting of absent, decreased, or ineffective PTH hormone, the body loses this regulatory function, and calcium imbalance ensues, and calcium imbalance can lead to osteoporosis.
- Physical trauma – surgery can occasionally result in the destruction of the parathyroid glands or kidneys. In neck dissection for head and neck cancers or inadvisable plastic surgery.
- Heavy metals – particularly exposure to mercury, lead etc Aluminium can also cause problems by affecting calcium balance."A strong association between cadmium and lead with bone disease has been established. Low-level exposure to cadmium is associated with an increased loss of bone mineral density readily in both genders, leading to pain and increased risk of fractures, especially in the elderly and in females. Higher cadmium exposure results in osteomalacia (softening of the bone)"
- Mineral supplements – people who take mineral supplements often overdose on magnesium, and magnesium in excess depletes calcium and lack of calcium causes osteoporosis
- Toxins – Many toxins can cause osteoporosis.
- Underweight/inactive: - In one of the ironies of this disease, being thin or underweight is a contributoy factor. Being thin could of course simply indicate nutritional deprivation, but it appears that bone remodeling occurs in response to physical stress, so weight bearing exercise or having to carry around your own plump self can increase and preserve bone - a highly significant correlation between bone strength and muscle strength has been determined. The incidence of osteoporosis is lower in overweight people. It would appear that fat people are not osteoporotic people
- Organ damage - whether by disease or by surgery other organ damage can also cause osteoporosis, this includes the reproductive organs - testosterone and its loss is also a cause of bone loss in men, for example
Secondary causes of bone loss are not often considered in patients who are diagnosed as having osteoporosis. In some studies, 20% to 30% of postmenopausal women and more than 50% of men with osteoporosis have a secondary cause. There are numerous causes of secondary bone loss, including adverse effects of drug therapy, endocrine disorders, eating disorders, immobilization, marrow-related disorders, disorders of the gastrointestinal or biliary tract, renal disease, and cancer. Patients who have undergone organ transplantation are also at increased risk for osteoporosis. PMID: 12004995
Find the cause. Although the pharmaceutical industry have been quick to bring out drugs to 'treat' osteoporosis, it is better to find out why it is happening - see Healing yourself.
Osteoporosis drugs do not have a good record for efficacy or safety. With some medications, half stop their medications within a year. For example, Calcitonin while once recommended is no longer due to the associated risk of cancer with its use and questionable effect on fracture risk.
How it works
Most of the hallucinations and visions are the result of the osteoporosis drugs.
In terms of healing, I have provided a range of observations from Pubmed that show the various foods that have been shown to be helpful.
- Allspice and the menopause 006911
- Association between dietary phytoestrogen intake and bone mineral density varied with estrogen receptor alpha gene polymorphisms in southern Chinese postmenopausal women 017885
- Benefits of moderate beer consumption at different stages of life of women 017884
- Benefits of prunes 006752
- Bioactivation of Phytoestrogens: Intestinal Bacteria and Health 017888
- Black cohosh and osteoporosis 017878
- Blueberries and health 005407
- Cod liver oil as both preventative and healing medicine 012188
- Dairy products and osteoporosis 005634
- Dr Duke's list of activity for the chemical Daidzein 017895
- Dr Duke's list of biological activities for Vitamin C 017880
- Dr Duke's list of plants having high concentrations of Estrogenic activity 017893
- Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women 017971
- Fermented soybeans by Rhizopus oligosporus reduce femoral bone loss in ovariectomized rats 017889
- Functional components and medicinal properties of food: a review 017887
- Intake of Novel Red Clover Supplementation for 12 Weeks Improves Bone Status in Healthy Menopausal Women 017918
- Lack of sunlight, osteoporosis and obesity 006225
- Osteopathy and osteoporosis 006194
- Osteoporosis and anise 006261
- Physical benefits of dancing for older adults 013365
- Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy 017922
- Reasoning for seasoning 005551
- Research progress of phytoestrogens-like chemical constituents in natural medicines 017886
- Royal jelly and osteoporosis 005344
- Screening for estrogenic and antiestrogenic activities of plants growing in Egypt and Thailand 017892
- Sunlight and health 006223
- Taking an integrated approach: managing women with phytoestrogens 017919
- The pros and cons of plant estrogens for menopause 017881
- Therapeutics Education Collaboration - Bohemian Polypharmacy 012489
Wisdom, Inspiration, Divine love & Bliss
Out of time
- Actonel hallucinations 006843
- Alendronate sodium 015640
- Calcitrol hallucinations 006838
- Effects of glucocorticoids on mood, memory, and the hippocampus. Treatment and preventive therapy 017713
- Etidronate disodium hallucinations 006844
- Forteo hallucinations 006842
- Fosamax hallucinations 006845
- Mineral imbalance and its repercussions 006922
- Nandrolone 017370
- Osteoporosis treatment produces psychosis 006741
- Pamidronic acid hallucinations 006840
- Premarin and Pempro 015668
- Reclast 015691
- Vitamin D supplement hallucinations 006839
- Zometa hallucinations 006841